Single-cell Sequencing and Methylation
Author | : Buwei Yu |
Publisher | : Springer |
Total Pages | : 247 |
Release | : 2020-10-14 |
ISBN-10 | : 981154493X |
ISBN-13 | : 9789811544934 |
Rating | : 4/5 (3X Downloads) |
Book excerpt: With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.