CH—Acids
Author | : O. A. Reutov |
Publisher | : Elsevier |
Total Pages | : 237 |
Release | : 2016-10-27 |
ISBN-10 | : 9781483163833 |
ISBN-13 | : 1483163830 |
Rating | : 4/5 (33 Downloads) |
Book excerpt: Ch-Acids deals with the acidity of all organic compounds containing C-H bonds. CH-acidity characterizes thermodynamic stability of carbanions in a medium containing a proton donor as carbanion acceptor. The book primarily explains proton transfer stereochemistry or structure in relation to CH-acidity patterns. Methods to study equilibrium acidity; tabulation of pKa values of CH-acids; and equilibrium acidity as a function of CH-acid structures are presented. Topics on kinetic CH-acidity; stereochemistry of proton transfer in CH-acids; and factors obscuring experimental observation of the action of the Bronsted equation are discussed extensively. The text will be of importance to organometallic and organic chemists.