Fundamentals of Molecular Biology

Book excerpt: Fundamentals of Molecular Biology is designed to serve as a syllabus-oriented textbook for undergraduate students of Biotechnology from JNTU, Anna University, BITS Pilani, WBUT etc. The focus is on explaining the basic concepts and techniques in molecular biology and their applications thereof. Starting with the definition and role of molecular biology, the book provides complete coverage of topics such as micro and macromolecule, DNA enzymes, the concept of genomes and various techniques used through its study and an overview of recombinant DNA technology and its applications. The book delves deeper into the subject by providing discussions on DNA replication, its damage, repair and recombination, transcription machinery in prokaryotes and eukaryotes, translation, protein folding, modifications and degradations, finally concluding with a detailed discussion on Genomics and Proteomics. The book is written in simple language aimed at helping students assimilate complex theories with ease. The text is complemented by a large number of diagrams, colour illustrations, and end-chapter questions. Key terms are highlighted in the text for students to grasp concepts quickly. Exhaustive references for further reading are provided at the end of every chapter for the interested reader.