Correlative Light and Electron MIcroscopy
Author | : Thomas Muller-Reichert |
Publisher | : Academic Press |
Total Pages | : 466 |
Release | : 2012-08-10 |
ISBN-10 | : 9780124160262 |
ISBN-13 | : 0124160263 |
Rating | : 4/5 (62 Downloads) |
Book excerpt: The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM) has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM, including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM. Covers many areas of CLEM by the best international scientists in the field Includes a brief history and overview on CLEM methods